Last updated: 2025-05-12 21657 annotations 43 curated publications
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Gene: rlc1 / SJAG_01665
Gene symbol
rlc1
Product
myosin II regulatory light chain Rlc1
Feature type
protein coding
Systematic ID
SJAG_01665
Product size
171 aa, 18.9 kDa
Genomic location
III, 2107942-2107427 (516nt) coding start to stop
2107942-2107427 (516nt) including UTRs
Predicted structure
Protein features
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Structure view loading ...
Target of
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Send causally upstream genes to the Advanced Search: Gene Ontology | Phenotype
Ontology Relationship Gene/genotype Product
fission_yeast_phenotype affected by mutation in mid1 anillin-related medial ring protein Mid1
fission_yeast_phenotype affected by mutation in pom1 DYRK family cell polarity protein kinase Pom1
Protein domains and features
Protein families and domains
Match ID Source Name InterPro ID Start End Count
PF13499 Pfam EF-hand domain IPR002048
36
81
PS00018 PROSITE_PATTERNS EF-Hand 1, calcium-binding site IPR018247
46
58
PS50222 PROSITE_PROFILES EF-hand domain IPR002048
33
68
SM00054 SMART EF-hand domain IPR002048
37
65
G3DSA:1.10.238.10:FF:000178 FUNFAM Calmodulin-2 A
27
168
SSF47473 SUPERFAMILY EF-hand domain pair IPR011992
30
165
G3DSA:1.10.238.10 Gene3D
17
102
98
170
PTHR23049 PANTHER Myosin regulatory light chain IPR050403
17
168
Domain organization at InterPro ...
No predicted trans-membrane domains
Protein properties
Molecular weight 18.9 kDa
Number of residues 171
Average residue weight 110 Da
Charge at pH 7 -4.79
Isoelectric point 4.73
Orthologs
Manually assigned orthologs
Ortholog species Ortholog gene Ortholog description Reference
Homo sapiens MYL9 (HGNC:15754) myosin light chain 9 Lock A et al. (2018)
Homo sapiens MYL12A (HGNC:16701) myosin light chain 12A Lock A et al. (2018)
Homo sapiens MYL7 (HGNC:21719) myosin light chain 7 Lock A et al. (2018)
Homo sapiens MYL11 (HGNC:29824) myosin light chain 11 Lock A et al. (2018)
Homo sapiens MYL10 (HGNC:29825) myosin light chain 10 Lock A et al. (2018)
Homo sapiens MYL12B (HGNC:29827) myosin light chain 12B Lock A et al. (2018)
Homo sapiens MYL2 (HGNC:7583) myosin light chain 2 Lock A et al. (2018)
Homo sapiens MYL5 (HGNC:7586) myosin light chain 5 Lock A et al. (2018)
Schizosaccharomyces pombe rlc1 (SPAC926.03) myosin II regulatory light chain Rlc1 Rhind N et al. (2011)
Saccharomyces cerevisiae MLC2 (YPR188C) Regulatory light chain for the type II myosin Myo1p more ... Lock A et al. (2018)
Ortholog prediction resources
Ensembl Fungal Compara SJAG_01665 Alignments, gene trees, orthologs, families
Ensembl Pan-taxonomic Compara SJAG_01665 Gene tree, orthologs
Transcript details
Key:
 
UTR
 
exon
mRNA SJAG_01665.1
myosin II regulatory light chain Rlc1
Location: 2107942-2107427 (516nt), chromosome III reverse strand     Product size: 171 aa, 18.9 kDa
 
Sequence
Manually select residues
>SJAG_01665.1 length:171
MTSKNKRLPKSLPSKLVTSKRINSGTFSQLTTSQIQELKEAFALLDKDGDGVVDRDDLKSMLTSLNQDASDEALDQMLSEVNPPINLASFLTAIGSMLCKISPRADLMEAFYTIEDTQSGKMSLRSFEEALSRSGSDIKGSELEDVIRPYTNHGTFYYEKFVNAIAGTKEN*
External references
GO annotation QuickGO B6JYK4 QuickGO Gene Ontology annotation viewer
GO annotation AmiGO SJAG_01665 GO Consortium browser
Interactions STRING B6JYK4 Network display of known and predicted interactions and functional associations
Sequence Resources UniProtKB/SwissProt B6JYK4 Protein database
Sequence Resources NCBI rlc1 Query all NCBI databases
Sequence Resources Ensembl SJAG_01665 Genome browser
Orthologs Ensembl Fungal Compara SJAG_01665 Alignments, gene trees, orthologs, families
Orthologs Ensembl Pan-taxonomic Compara SJAG_01665 Gene tree, orthologs
Literature
Search PubMed for rlc1
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Details Genes
Actin turnover maintains actin filament homeostasis during cytokinetic ring contraction.
Chew TG et al. J Cell Biol 2017 09 04;216(9):2657-2667 PMID:28655757 Curated details ...
5
Rewiring of cellular division site selection in evolution of fission yeasts.
Gu Y et al. Curr Biol 2015 May 04;25(9):1187-94 PMID:25866389 Curated details ...
8
PomBase: The Scientific Resource for Fission Yeast.
Lock A et al. Methods Mol Biol 2018;1757:49-68 PMID:29761456 details ...
4165
Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6 PMID:21511999 details ...
4284