Last updated: 2025-03-09 21626 annotations 42 curated publications
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Gene: tif213 / SJAG_00466
Gene symbol
tif213
Product
translation initiation factor eIF2 gamma subunit
Feature type
protein coding
Systematic ID
SJAG_00466
Product size
448 aa, 48.8 kDa
Genomic location
I, 3290898-3292244 (1347nt) coding start to stop
3290898-3292244 (1347nt) including UTRs
Predicted structure
Protein features
Genome browser
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Structure view loading ...
Protein domains and features
Protein families and domains
Match ID Source Name InterPro ID Start End Count
PF09173 Pfam Initiation factor eIF2 gamma, C-terminal IPR015256
351
440
PF00009 Pfam Translational (tr)-type GTP-binding domain IPR000795
23
226
PF03144 Pfam Translation elongation factor EFTu-like, domain 2 IPR004161
258
340
cd01888 CDD Initiation factor eIF2 gamma, GTP-binding domain IPR044128
24
230
cd03688 CDD Initiation factor eIF2 gamma, domain 2 IPR044127
231
344
cd15490 CDD Initiation factor eIF2 gamma, C-terminal IPR015256
347
440
PS51722 PROSITE_PROFILES Translational (tr)-type GTP-binding domain IPR000795
21
229
PR00315 PRINTS Translational (tr)-type GTP-binding domain IPR000795
25
176
G3DSA:2.40.30.10:FF:000009 FUNFAM Eukaryotic translation initiation factor 2 subunit gamma
231
346
G3DSA:2.40.30.10:FF:000011 FUNFAM Eukaryotic translation initiation factor 2 subunit gamma
347
445
G3DSA:3.40.50.300:FF:000065 FUNFAM Eukaryotic translation initiation factor 2 subunit gamma
21
230
SSF50465 SUPERFAMILY Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal IPR009001
345
440
SSF50447 SUPERFAMILY Translation protein, beta-barrel domain superfamily IPR009000
230
344
SSF52540 SUPERFAMILY P-loop containing nucleoside triphosphate hydrolase IPR027417
20
110
72
234
G3DSA:3.40.50.300 Gene3D P-loop containing nucleoside triphosphate hydrolase IPR027417
21
230
G3DSA:2.40.30.10 Gene3D Translation factors
231
446
PTHR42854 PANTHER Eukaryotic Initiation Factor 2 Gamma Subunit IPR050543
4
448
Domain organization at InterPro ...
No predicted trans-membrane domains
Protein properties
Molecular weight 48.8 kDa
Number of residues 448
Average residue weight 109 Da
Charge at pH 7 9.83
Isoelectric point 8.67
Disease association
Orthologs
Manually assigned orthologs
Ortholog species Ortholog gene Ortholog description Reference
Homo sapiens EIF2S3 (HGNC:3267) eukaryotic translation initiation factor 2 subunit gamma Lock A et al. (2018)
Schizosaccharomyces pombe tif213 (SPBC17G9.09) translation initiation factor eIF2 gamma subunit Rhind N et al. (2011)
Saccharomyces cerevisiae GCD11 (YER025W) Gamma subunit of the translation initiation factor eIF2 more ... Lock A et al. (2018)
Ortholog prediction resources
Ensembl Fungal Compara SJAG_00466 Alignments, gene trees, orthologs, families
Ensembl Pan-taxonomic Compara SJAG_00466 Gene tree, orthologs
Transcript details
Key:
 
UTR
 
exon
mRNA SJAG_00466.1
translation initiation factor eIF2 gamma subunit
Location: 3290898-3292244 (1347nt), chromosome I forward strand     Product size: 448 aa, 48.8 kDa
 
Sequence
Manually select residues
>SJAG_00466.1 length:448
MVEALDPTELTPVHPAIISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKCENPDCPRPGCYRSYSSNKEDEPLCEVPNCGHKMKLIRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNEPCPQPQTSEHLAAIEIMQLKHIIILQNKVDLIRESAAEEHYQSILKFIKGTVAENAPIVPISAQLKYNIDAILEYIVKKIPIPVRDFTSAPRLIVIRSFDVNKPGAGVEDLKGGVAGGSILTGVLHLGDEIEIRPGIVTKDDDGRIKCQPIFSRIVSLFAEHNDLKLAVPGGLIGVGTTVDPTLCRADRLVGQVLGSKGNLPEVYTELEINYFLLRRLLGVKSGDKNTTKVQKLAKNEVLMVNIGSTSTGGRVMMVKADLAKILLTAPACTEIGEKVALSRRIEKHWRLIGWAKVVEGKTLKV*
External references
GO annotation QuickGO B6JVQ1 QuickGO Gene Ontology annotation viewer
GO annotation AmiGO SJAG_00466 GO Consortium browser
Interactions STRING B6JVQ1 Network display of known and predicted interactions and functional associations
Sequence Resources UniProtKB/SwissProt B6JVQ1 Protein database
Sequence Resources NCBI tif213 Query all NCBI databases
Sequence Resources Ensembl SJAG_00466 Genome browser
Orthologs Ensembl Fungal Compara SJAG_00466 Alignments, gene trees, orthologs, families
Orthologs Ensembl Pan-taxonomic Compara SJAG_00466 Gene tree, orthologs
Literature
Search PubMed for tif213
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Details Genes
PomBase: The Scientific Resource for Fission Yeast.
Lock A et al. Methods Mol Biol 2018;1757:49-68 PMID:29761456 details ...
4165
Comparative functional genomics of the fission yeasts.
Rhind N et al. Science 2011 May 20;332(6032):930-6 PMID:21511999 details ...
4284